Combination therapy using evening primrose oil and electrical stimulation to improve nerve function following a crush injury of sciatic nerve in male rats

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p11: evening primrose oil improves nerve functions following crush injury of sciatic nerve in rats

repairing the damaged nerves caused by physical injury (trauma), is one of the major challenges facing modern medical sciences. evening primrose oil (epo) extraction of oenothera biennis seed that enriches with omega-6,γ-linoleic acid and linoleic acid that they have essential role in myelination and neural membrane structure. the aim of this study was to evaluate the functional recovery of sci...

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The Changes in Rats with Sciatic Nerve Crush Injury Supplemented with Evening Primrose Oil: Behavioural, Morphologic, and Morphometric Analysis

Nerve crush injuries are commonly used models for axonotmesis to examine peripheral nerve regeneration. As evening primrose oil (EPO) is rich in omega-6 essential fatty acid component and gamma-linolenic acid, studies have shown the potential role of EPO in myelination. Seventy-two healthy adult Sprague-Dawley rats were classified into three groups: normal group, control group, and experimental...

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Gallic acid and exercise training improve motor function, nerve conduction velocity but not pain sense reflex after experimental sciatic nerve crush in male rats

Objective: The aim of present study was to evaluate the effects of oral administration of gallic acid (GA) for 21 days alone and in combination with exercise on nerve conduction velocity and sensory and motor functions in rats with sciatic nerve crush. Materials and Methods: Seventy adult male Wistar rats (250-300 g) were divided randomly into 7 groups with 10 in each: 1) Control (Cont), 2) Cru...

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Sciatic functional index following induction of injury in the sciatic nerve of rats

Sciatic functional index (SFI) as a behavioral method was used to assess the functional recovery following experimentally-induced various injuries in the sciatic nerve, spinal cord, and brain. In the present study, the functional recovery after induction of injury in the sciatic nerve was investigated in rats using SFI. Twenty-four rats were divided into three groups including sham-operated (SS...

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ژورنال

عنوان ژورنال: Neural Regeneration Research

سال: 2017

ISSN: 1673-5374

DOI: 10.4103/1673-5374.202927